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A RANDOMIZED, DOUBLE-BLIND, PARALLEL-FILTER STUDY TO EVALUATE THE ANTIHYPERTENSIVE EFFICACY AND SAFETY OF LOSARTAN-HCTZ
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Efficacy, safety, and tolerability of valsartan/hydrochlorothiazide in Asian patients with Both losartan/HCTZ and losartan alone significantly reduced SiDBP and
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We aimed to assess the efficacy and safety of losartan 100 mg as monotherapy or in fixed-dose combination with hydrochlorothiazide 25 mg. Design and
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T/HCTZ also produced significantly greater reductions than V/HCTZ in 24-hour mean . Safety. The overall incidence of adverse events was low with at least one antihypertensives, such as ramipril [21-23], losartan [24,25], and valsartan [9].
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Comparison of the Efficacy and Safety of Single-Pill Fixed-Dose Combinations of Losartan/Hydrochlorothiazide and Valsartan/Hydrochlorothiazide in Patients
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assessed with Student's t-test for independent samples. Safety. • Nine SAEs were reported for 8 patients: losartan/HCTZ (n=4) and valsartan/HCTZ (n=4).
Efficacy and safety of losartan 100 mg or losartan 100 mg plus hydrochlorothiazide 25 mg in the treatment of patients with essential arterial
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Safety. Lightheadedness may occur with losartan-hydrochlorothiazide treatment, especially during the first days of therapy. If syncope occurs
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